Altered Lipid Metabolism in Residual White Adipose Tissues of Bscl2 Deficient Mice
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چکیده
منابع مشابه
Altered Lipid Metabolism in Residual White Adipose Tissues of Bscl2 Deficient Mice
Mutations in BSCL2 underlie human congenital generalized lipodystrophy type 2 disease. We previously reported that Bscl2 (-/-) mice develop lipodystrophy of white adipose tissue (WAT) due to unbridled lipolysis. The residual epididymal WAT (EWAT) displays a browning phenotype with much smaller lipid droplets (LD) and higher expression of brown adipose tissue marker proteins. Here we used target...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0082526